Xudong Wu Selected Research

Glioblastoma (Glioblastoma Multiforme)

4/2024	A LATS2 and ALKBH5 positive feedback loop supports their oncogenic roles.
1/2024	Hypoxia-inducible PRMT2 addiction in glioblastomas.
1/2022	JUN activation modulates chromatin accessibility to drive TNFα-induced mesenchymal transition in glioblastoma.
12/2021	ALKBH5 Facilitates Hypoxia-Induced Paraspeckle Assembly and IL8 Secretion to Generate an Immunosuppressive Tumor Microenvironment.
1/2021	Circular RNA circNF1 siRNA Silencing Inhibits Glioblastoma Cell Proliferation by Promoting the Maturation of miR-340.
1/2020	Glioblastoma Immunotherapy Targeting the Innate Immune Checkpoint CD47-SIRPα Axis.
9/2019	Genome-Wide CRISPR-Cas9 Screening Identifies NF-κB/E2F6 Responsible for EGFRvIII-Associated Temozolomide Resistance in Glioblastoma.
10/2018	PRMT2 links histone H3R8 asymmetric dimethylation to oncogenic activation and tumorigenesis of glioblastoma.
1/2018	Targeting of BMI-1 with PTC-209 inhibits glioblastoma development.

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Xudong Wu Research Topics

Disease

25	Neoplasms (Cancer) 04/2024 - 01/2006
10	Inflammation (Inflammations) 08/2023 - 12/2015
9	Glioblastoma (Glioblastoma Multiforme) 04/2024 - 01/2018
8	Colitis 02/2024 - 06/2014
7	Carcinogenesis 04/2024 - 01/2006
5	Body Weight (Weight, Body) 01/2022 - 01/2016
5	Insulin Resistance 01/2020 - 05/2017
4	Stomach Neoplasms (Stomach Cancer) 01/2021 - 01/2019
4	Sepsis (Septicemia) 01/2020 - 05/2014
3	Hypoxia (Hypoxemia) 01/2024 - 12/2021
3	Psoriasis (Pustulosis Palmaris et Plantaris) 01/2023 - 12/2018
3	Non-alcoholic Fatty Liver Disease 01/2023 - 06/2008
3	COVID-19 01/2022 - 01/2020
3	Colorectal Neoplasms (Colorectal Cancer) 11/2020 - 10/2014
3	Obesity 04/2020 - 05/2017
3	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 11/2016 - 07/2014
3	Ischemia 01/2008 - 07/2006
2	Liver Cirrhosis (Hepatic Cirrhosis) 01/2023 - 11/2016
2	Deafness (Deaf Mutism) 01/2023 - 01/2017
2	Fibrosis (Cirrhosis) 01/2023 - 11/2016
2	Myocardial Ischemia (Ischemic Heart Diseases) 12/2020 - 05/2007
2	Hemorrhage 01/2020 - 01/2020
2	Polycystic Kidney Diseases (Polycystic Kidney Disease) 01/2019 - 08/2011
2	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2018 - 06/2014
2	Contact Dermatitis (Eczema, Contact) 09/2015 - 11/2014
2	Diarrhea 12/2014 - 07/2014
2	Hypertension (High Blood Pressure) 02/2009 - 03/2003
1	Periodontitis 05/2024
1	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 02/2024
1	Hypoalbuminemia 01/2024
1	Glioma (Gliomas) 01/2024
1	Neoplasms, Cystic, Mucinous, and Serous 01/2024
1	Cholangitis 08/2023
1	Choledocholithiasis 08/2023
1	Atrophy 01/2023

Drug/Important Bio-Agent (IBA)

12	Proteins (Proteins, Gene)FDA Link 04/2024 - 08/2011
8	CytokinesIBA 01/2022 - 05/2014
5	Long Noncoding RNAIBA 01/2022 - 01/2019
4	6-methyladenineIBA 04/2024 - 12/2021
4	Dextran SulfateIBA 01/2023 - 06/2014
4	InflammasomesIBA 01/2022 - 06/2014
3	Phosphotransferases (Kinase)IBA 04/2024 - 07/2006
3	EnzymesIBA 01/2023 - 01/2016
3	RNA (Ribonucleic Acid)IBA 01/2023 - 04/2020
3	MicroRNAs (MicroRNA)IBA 01/2022 - 12/2012
3	Messenger RNA (mRNA)IBA 01/2022 - 01/2020
3	salicylhydroxamic acid (SHAM)IBA 12/2020 - 07/2006
3	HIV Protease InhibitorsIBA 12/2014 - 07/2009
2	Histones (Histone)IBA 04/2024 - 10/2018
2	Metformin (Glucophage)FDA LinkGeneric 02/2024 - 01/2018
2	Oxygen (Dioxygen)IBA 01/2024 - 01/2020
2	Imiquimod (Aldara)FDA LinkGeneric 01/2023 - 01/2019
2	Dexamethasone (Maxidex)FDA LinkGeneric 01/2023 - 11/2014
2	LipopolysaccharidesIBA 10/2022 - 05/2017
2	Biomarkers (Surrogate Marker)IBA 01/2022 - 01/2019
2	ChromatinIBA 01/2022 - 06/2008
2	Circular RNAIBA 01/2022 - 01/2021
2	Polycomb-Group ProteinsIBA 01/2021 - 01/2006
2	Oxidoreductases (Dehydrogenase)IBA 01/2021 - 03/2014
2	Fatty Acids (Saturated Fatty Acids)IBA 04/2020 - 05/2017
2	C-Reactive ProteinIBA 01/2020 - 01/2020
2	Glucose (Dextrose)FDA LinkGeneric 01/2020 - 05/2017
2	Phenobarbital (Luminal)FDA Link 01/2020 - 02/2009
2	Insulin (Novolin)FDA Link 01/2020 - 05/2017
2	Carcinoembryonic AntigenIBA 01/2020 - 01/2020
2	Nonesterified Fatty Acids (NEFA)IBA 10/2019 - 06/2008
2	ErbB Receptors (EGF Receptor)IBA 09/2019 - 12/2014
2	AutoantibodiesIBA 01/2019 - 01/2015
2	Amino Acids FDA Link 01/2019 - 01/2016
2	Interleukin-17 (Interleukin 17)IBA 12/2018 - 09/2015
2	Tyrosine Kinase InhibitorsIBA 12/2018 - 12/2014
2	astilbinIBA 01/2018 - 01/2015
2	NLR ProteinsIBA 05/2017 - 12/2015
2	Calcium-Transporting ATPases (Ca2+ ATPase)IBA 01/2017 - 10/2014
2	andrographolideIBA 11/2016 - 06/2014
2	limoninIBA 01/2016 - 09/2015
2	CurcuminIBA 11/2015 - 10/2014
2	Immunosuppressive Agents (Immunosuppressants)IBA 09/2015 - 01/2015
2	Interleukin-2 (IL2)IBA 09/2015 - 11/2014
2	p38 Mitogen-Activated Protein KinasesIBA 05/2007 - 07/2006
1	sinensetinIBA 05/2024
1	protein arginine methyltransferase 2IBA 01/2024
1	MethyltransferasesIBA 01/2024
1	ElectrolytesIBA 01/2024
1	Transcription Factors (Transcription Factor)IBA 01/2024
1	SphingolipidsIBA 01/2023
1	Bile Acids and Salts (Bile Acids)IBA 01/2023
1	OvalbuminIBA 01/2023

Therapy/Procedure

12	Therapeutics 11/2023 - 12/2014
5	Ligation 05/2024 - 05/2014
4	Immunotherapy 11/2023 - 12/2015
3	Drug Therapy (Chemotherapy) 01/2022 - 12/2014
3	Punctures 01/2020 - 05/2014
2	Radiotherapy 11/2023 - 01/2022
2	Laparotomy 01/2020 - 01/2020
2	Lymph Node Excision (Lymph Node Dissection) 01/2020 - 01/2020
2	Operative Time 01/2020 - 01/2020
2	Highly Active Antiretroviral Therapy (HAART) 12/2014 - 03/2013
1	Hyperthermic Intraperitoneal Chemotherapy 01/2024
1	Surgical Instruments (Clip) 08/2023